T cell activation induces proteasomal degradation of argonaute and rapid remodeling of the microRNA repertoire

Autor: Erle, David, Ansel, Karl, McManus, Thomas, Bronevetsky, Y, Villarino, AV, Eisley, CJ, Barbeau, R, Barczak, AJ, Heinz, GA, Kremmer, E, Heissmeyer, V, McManus, MT, Erle, DJ
Jazyk: angličtina
Rok vydání: 2013
Zdroj: Erle, David; Ansel, Karl; McManus, Thomas; Bronevetsky, Y; Villarino, AV; Eisley, CJ; et al.(2013). T cell activation induces proteasomal degradation of argonaute and rapid remodeling of the microRNA repertoire. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/2361s4kw
Popis: Activation induces extensive changes in the gene expression program of naive CD4+ T cells, promoting their differentiation into helper T cells that coordinate immune responses. MicroRNAs (miRNAs) play a critical role in this process, and miRNA expression a
Databáze: OpenAIRE