| Autor: |
Finer, N N, Carlo, W A, Duara, S, Fanaroff, A A, Donovan, E F, Wright, L L, Kandefer, S, Poole, W K |
| Jazyk: |
angličtina |
| Rok vydání: |
2004 |
| Předmět: |
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| Zdroj: |
Finer, N N; Carlo, W A; Duara, S; Fanaroff, A A; Donovan, E F; Wright, L L; et al.(2004). Delivery room continuous positive airway pressure/positive end-expiratory pressure in extremely low birth weight infants: A feasibility trial. Pediatrics, 114(3), 651-657. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/4vt4m2mv |
| Popis: |
Objective. Although earlier studies have suggested that early continuous airway positive pressure (CPAP) may be beneficial in reducing ventilator dependence and subsequent chronic lung disease in the extremely low birth weight (ELBW) infant, the time of initiation of CPAP has varied, and there are no prospective studies of infants who have received CPAP or positive end-expiratory pressure (PEEP) from initial resuscitation in the delivery room (DR). Current practice for the ELBW infant includes early intubation and the administration of prophylactic surfactant, often in the DR. The feasibility of initiating CPAP in the DR and continuing this therapy without intubation for surfactant has never been determined prospectively in a population of ELBW infants. This study was designed to determine the feasibility of randomizing ELBW infants of 0.3 with an oxygen saturation by pulse oximeter of 55 mm Hg, or apnea requiring bag and mask ventilation. Results. A total of 104 infants were enrolled over a 6-month period: 55 CPAP and 49 control infants. No infant was intubated in the DR for the exclusive purpose of surfactant administration. Forty-seven infants were intubated for resuscitation in the DR: 27 of 55 CPAP infants and 20 of 49 control infants. Only 4 of the 43 infants who had a birth weight of |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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