A panel of CpG methylation sites distinguishes human embryonic stem cells and induced pluripotent stem cells

Autor: Shen, Yin, Huang, K, Xue, Z, Bibikova, M, April, C, Liu, Z, Cheng, L, Nagy, A, Pellegrini, M, Fan, JB
Jazyk: angličtina
Rok vydání: 2014
Zdroj: Shen, Yin; Huang, K; Xue, Z; Bibikova, M; April, C; Liu, Z; et al.(2014). A panel of CpG methylation sites distinguishes human embryonic stem cells and induced pluripotent stem cells. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/85w6w27m
Popis: Whether human induced pluripotent stem cells (hiPSCs) are epigenetically identical to human embryonic stem cells (hESCs) has been debated in the stem cell field. In this study, we analyzed DNA methylation patterns in a large number of hiPSCs (n = 114) and
Databáze: OpenAIRE