Macrophage-specific apoE gene repair reduces diet-induced hyperlipidemia and atherosclerosis in hypomorphic apoE mice

Autor: Rapp, Joseph, Raffai, Robert, Gaudreault, N, Kumar, N, Olivas, VR, Eberlé, D, Rapp, JH, Raffai, RL
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Rapp, Joseph; Raffai, Robert; Gaudreault, N; Kumar, N; Olivas, VR; Eberlé, D; et al.(2012). Macrophage-specific apoE gene repair reduces diet-induced hyperlipidemia and atherosclerosis in hypomorphic apoE mice. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/2768c3g2
Popis: Background: Apolipoprotein (apo) E is best known for its ability to lower plasma cholesterol and protect against atherosclerosis. Although the liver is the major source of plasma apoE, extra-hepatic sources of apoE, including from macrophages, account for
Databáze: OpenAIRE