Autor: |
Larson, SB, Day, JS, Nguyen, C, Cudney, R, McPherson, A |
Jazyk: |
angličtina |
Rok vydání: |
2010 |
Zdroj: |
Larson, SB; Day, JS; Nguyen, C; Cudney, R; & McPherson, A. (2010). Structure of bovine pancreatic ribonuclease complexed with uridine 5′-monophosphate at 1.60 Å resolution. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 66(2), 113-120. doi: 10.1107/S174430910905194X. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7w96z9kk |
DOI: |
10.1107/S174430910905194X. |
Popis: |
Bovine pancreatic ribonuclease A (RNase A) was crystallized from a mixture of small molecules containing basic fuchsin, tobramycin and uridine 5′-monophos-phate (U5P). Solution of the crystal structure revealed that the enzyme was selectively bound to U5P, with the pyrimidine ring of U5P residing in the pyrimidine-binding site at Thr45. The structure was refined to an R factor of 0.197 and an Rfree of 0.253. © 2010 International Union of Crystallography All rights reserved. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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