| Autor: |
Franceschini, MA, Moesta, KT, Fantini, S, Gaida, G, Gratton, E, Jess, H, Mantulin, WW, Seeber, M, Schlag, PM, Kaschke, M |
| Jazyk: |
angličtina |
| Rok vydání: |
1997 |
| Předmět: |
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| Zdroj: |
Franceschini, MA; Moesta, KT; Fantini, S; Gaida, G; Gratton, E; Jess, H; et al.(1997). Frequency-domain techniques enhance optical mammography: Initial clinical results. Proceedings of the National Academy of Sciences of the United States of America, 94(12), 6468-6473. doi: 10.1073/pnas.94.12.6468. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/4rp1z2z3 |
| DOI: |
10.1073/pnas.94.12.6468. |
| Popis: |
We present a novel approach to optical mammography and initial clinical results. We have designed and developed a frequency-domain (110-MHz) optical scanner that performs a transillumination raster scan of the female breast in approximately 3 min. The probing light is a dual-wavelength (690 and 810 nm, 10-mW average power), 2-mm-diameter laser beam, and the detection optical fiber is 5 mm in diameter. The ac amplitude and phase data are processed with use of an algorithm that performs edge effect corrections, thereby enhancing image contrast. This contrast enhancement results in a greater tumor detectability compared with simple light intensity images. The optical mammograms are displayed on a computer screen in real time. We present x-ray and optical mammograms from two patients with breast tumors. Our initial clinical results show that the frequency-domain scanner, even at the present stage of development, has the potential to be a useful tool in mammography. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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