| Autor: |
Mener, David J, Betz, Joshua, Yaffe, Kristine, Harris, Tamara B, Helzner, Elizabeth P, Satterfield, Suzanne, Houston, Denise K, Strotmeyer, Elsa S, Pratt, Sheila R, Simonsick, Eleanor M, Lin, Frank R, Health ABC Study |
| Rok vydání: |
2016 |
| Předmět: |
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| Zdroj: |
American journal of Alzheimer's disease and other dementias, vol 31, iss 1 |
| Popis: |
BackgroundWhether apolipoprotein E (APOE) E4 allele status which is associated with an increased risk of cognitive decline is also associated with hearing impairment is unknown.MethodsWe studied 1833 men and women enrolled in the Health, Aging and Body Composition study. Regression models adjusted for demographic and cardiovascular risk factors were used to assess the cross-sectional association of APOE-E4 status with individual pure tone hearing thresholds and the 4-frequency pure tone average (0.5-4 kHz) in the better hearing ear.ResultsCompared to participants with no APOE-E4 alleles, participants with 1 allele had better thresholds at 4.0 kHz (β = -2.72 dB, P = .013) and 8.0 kHz (β = -3.05 kHz, P = .006), and participants with 2 alleles had better hearing thresholds at 1.0 kHz (β = -8.56 dB, P = .021).ConclusionOur results suggest that APOE-E4 allele status may be marginally associated with better hearing thresholds in older adults. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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