Urine Biomarkers of Kidney Tubule Health and Incident CKD Stage 3 in Women Living With HIV: A Repeated Measures Study

Autor: Ascher, Simon B, Scherzer, Rebecca, Estrella, Michelle M, Jotwani, Vasantha K, Shigenaga, Judy, Spaulding, Kimberly A, Ng, Derek K, Gustafson, Deborah, Spence, Amanda B, Sharma, Anjali, Cohen, Mardge H, Parikh, Chirag R, Ix, Joachim H, Shlipak, Michael G
Rok vydání: 2021
Předmět:
Zdroj: Kidney medicine, vol 3, iss 3
Popis: Rationale & objectiveSingle measurements of urinary biomarkers reflecting kidney tubule health are associated with chronic kidney disease (CKD) risk in HIV infection, but the prognostic value of repeat measurements over time is unknown.Study designCohort study.Setting & participants647 women living with HIV infection enrolled in the Women's Interagency Health Study.Exposures14 urinary biomarkers of kidney tubule health measured at 2 visits over a 3-year period.OutcomeIncident CKD, defined as estimated glomerular filtration rate (eGFR) 
Databáze: OpenAIRE