Autor: |
Verkman, Alan, Coffman, KC, Nguyen, HH, Phuan, PW, Hudson, BM, Yu, GJ, Bagdasarian, AL, Montgomery, D, Lodewyk, MW, Yang, B, Yoo, CL |
Jazyk: |
angličtina |
Rok vydání: |
2014 |
Předmět: |
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Zdroj: |
Verkman, Alan; Coffman, KC; Nguyen, HH; Phuan, PW; Hudson, BM; Yu, GJ; et al.(2014). Constrained bithiazoles: Small molecule correctors of defective δf508-CFTR protein trafficking. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/4gh0h4d7 |
Popis: |
Conformationally constrained bithiazoles were previously found to have improved efficacy over nonconstrained bithiazoles for correction of defective cellular processing of the δF508 mutant cystic fibrosis transmembrane conductance regulator (CFTR) protein. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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