Remdesivir for the Prevention of Invasive Mechanical Ventilation or Death in Coronavirus Disease 2019 (COVID-19): A Post Hoc Analysis of the Adaptive COVID-19 Treatment Trial-1 Cohort Data

Autor: Paules, Catharine I, Gallagher, Shannon K, Rapaka, Rekha R, Davey, Richard T, Doernberg, Sarah B, Grossberg, Robert, Hynes, Noreen A, Ponce, Philip O, Short, William R, Voell, Jocelyn, Wang, Jing, Yang, Otto O, Wolfe, Cameron R, Lye, David C, Dodd, Lori E, Benson, Constance A
Rok vydání: 2022
Předmět:
Zdroj: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, vol 74, iss 7
Popis: This post hoc analysis of the Adaptive Coronavirus Disease 2019 (COVID-19) Treatment Trial-1 (ACTT-1) shows a treatment effect of remdesivir (RDV) on progression to invasive mechanical ventilation (IMV) or death. Additionally, we create a risk profile that better predicts progression than baseline oxygen requirement alone. The highest risk group derives the greatest treatment effect from RDV.
Databáze: OpenAIRE