Estrogen receptor antagonists are anti-cryptococcal agents that directly bind EF hand proteins and synergize with fluconazole in vivo

Autor: Madhani, Hiten, Butts, A, Koselny, K, Chabrier-Roselló, Y, Semighini, CP, Brown, JCS, Wang, X, Annadurai, S, DiDone, L, Tabroff, J, Childers, WE
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Madhani, Hiten; Butts, A; Koselny, K; Chabrier-Roselló, Y; Semighini, CP; Brown, JCS; et al.(2014). Estrogen receptor antagonists are anti-cryptococcal agents that directly bind EF hand proteins and synergize with fluconazole in vivo. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/7xg076bk
Popis: Cryptococcosis is an infectious disease of global significance for which new therapies are needed. Repurposing previously developed drugs for new indications can expedite the translation of new therapies from bench to beside. Here, we characterized the ant
Databáze: OpenAIRE