Rapamycin induces glucose intolerance in mice by reducing islet mass, insulin content, and insulin sensitivity

Autor: Young, David, Jan, Lily, Jan, Yuh, Yang, SB, Lee, HY, Young, DM, Tien, AC, Rowson-Baldwin, A, Shu, YY, Jan, YN, Jan, LY
Jazyk: angličtina
Rok vydání: 2012
Zdroj: Young, David; Jan, Lily; Jan, Yuh; Yang, SB; Lee, HY; Young, DM; et al.(2012). Rapamycin induces glucose intolerance in mice by reducing islet mass, insulin content, and insulin sensitivity. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/8zd5w0zf
Popis: Rapamycin, a specific inhibitor for mTOR complex 1, is an FDA-approved immunosuppressant for organ transplant. Recent developments have raised the prospect of using rapamycin to treat cancer or diabetes and to delay aging. It is therefore important to asse
Databáze: OpenAIRE