Eugenol derivatives with potential insecticide activity
| Autor: | Coelho, José Ricardo Alves, Fernandes, Maria José Gomes, Pereira, David M., Castanheira, Elisabete M. S., Fortes, A. Gil, Gonçalves, M. Sameiro T. |
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| Přispěvatelé: | Universidade do Minho |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Popis: | In the present work, semisynthetic eugenol derivatives were obtained through epoxidation reaction followed by epoxide opening with nucleophiles, such as sodium azide and sodium cyanide. The optimization of the various reactions was performed using different experimental conditions. The main objective behind obtaining these eugenol derivatives was their evaluation as alternative insecticides, thus the biological activity of all compounds was compared to a commercial synthetic insecticide and tested against Sf9 (Spodoptera frugiperda) insect cell line. We thank the financial support of project PTDC/ASP-AGR/30154/2017 (POCI-01-0145-FEDER-030154) of the COMPETE 2020 program, co-financed by the FEDER and the European Union. The authors acknowledge also to Foundation for Science and Technology (FCT, Portugal), and FEDER-COMPETE-QREN-EU for financial support to the research centres CQ-UM (UID/QUI/00686/2020), CF-UM-UP (UID/FIS/04650/2020) and REQUIMTE (UIDB/50006/2020). The NMR spectrometer Bruker Avance III 400 is part of the National NMR Network and was purchased within the framework of the National Program for Scientific Re-equipment, contract REDE/1517/RMN/2005 with funds from POCI 2010 (FEDER) and FCT. |
| Databáze: | OpenAIRE |
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