| Autor: |
Deichert, Julie Amanda, Mizufune, Hideya, Patel, Jignesh J., Hurst, Timothy E., Maheta, Ashish, Kitching, Matthew, Ross, Avena, Snieckus, Victor |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| DOI: |
10.1002/ejoc.202000424 |
| Popis: |
The general synthesis of diversely substituted dibenzoxepinones by a combined Pd‐catalyzed α‐arylation and SNAr strategy is reported and applied to the synthesis of Manske's ketone, a key intermediate en route to the total synthesis of cularine alkaloids. In the course of this work, an unanticipated ring contraction reaction to a xanthone was observed and serves as a caveat for the conditions of the widely used α‐arylation reaction. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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