| Autor: |
Doerrfuss, J.I., Abdul-Rahim, A.H., Siegerink, B., Nolte, C.H., Lees, K.R., Endres, M., Kasner, S.E., Scheitz, J.F., Hanley, D.F., Butcher, K.S., Davis, S., Gregson, B., Lyden, P., Mayer, S., Muir, K., Sandset, E.C., Steiner, T., VISTA Collaboration |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Popis: |
Introduction Recent data suggest that statin use after intracerebral haemorrhage might be beneficial. However, data on the effects of early in-hospital statin exposure are lacking. Therefore, we sought to assess whether (1) early statin exposure during the acute phase after intracerebral haemorrhage and (2) early continuation of prevalent statin use are associated with favourable functional outcome. Patients and methods Data were obtained from the Virtual International Stroke Trials Archive. Patients were categorised according to use patterns of statins during this early in-hospital phase (continuation, discontinuation or new initiation of statins). Univariate and multivariable analyses were conducted to explore the association between early statin exposure and functional outcome. Results A total of 919 patients were included in the analysis. Early in-hospital statin exposure (n = 89, 9.7%) was associated with better functional outcome (modified Rankin Scale |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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