Functionalization of adhesion sites for cell attachment on a silicon microsystem

Autor:	Anker, Rebekka
Přispěvatelé:	Hausherr, Tanja Cloé, Yamahata, Christophe, Pioletti, Dominique, Gijs, Martinus
Předmět:	Mechanobiology finished Functionalized adhesion sites Mesenchymal stem cells (MSC) Bio-MEMS Silicon microsystem Fibroblasts
Popis:	Mesenchymal Stem Cells (MSC) are multipotent adult stem cells that are predominantly obtained from the bone marrow. MSC have a high ability to differentiate into a multitude of cell types that are very attractive for tissue engineering. To study the effects of mechanical strain on this kind of cells, we have developed a silicon microsystem (see the photograph below). The main objective of this semester project will be to create functionalized adhesion sites for fibroblasts and MSC attachment on a silicon device. First, the student will have to find and test different methods which could be used to promote single-cell adhesion on silicon. Then, he will have to adapt this method to our system and perform preliminary tests with fibroblasts.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=od_______185::ba87e44a509b272a99d64dbf208bbe3d https://infoscience.epfl.ch/record/170358 Zobrazit plný text záznamu