| Autor: |
Avanzi, Charlotte, Maia, Raquel Cristina, Benjak, Andrej, Nery, Jose Augusto, Sales, Anna Maria, Miranda, Alice, Duppre, Nadia Cristina, Fontes, Amanda Nogueira Brum, da Silva, Tatiana Pereira, Pinheiro, Roberta Olmo, Neves-manta, Fernanda, Moreira, Suelen Justo Maria, Busso, Philippe, Sarno, Euzenir Nunes, Suffys, Phillip Noel, Cole, Stewart Thomas, Moraes, Milton Ozorio |
| Předmět: |
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| Popis: |
A case of Mycobacterium leprae rifampin resistance after irregular antile- prosy treatments since 1971 is reported. Whole-genome sequencing from four longi- tudinal samples indicated relapse due to acquired rifampin resistance and not to re- infection with another strain. A putative compensatory mutation in rpoC was also detected. Clinical improvement was achieved using an alternative therapy. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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