| Autor: |
Lagarde, Henri, Lallias, Delphine, Patrice, Pierre, Prchal, Martin, François, Yoannah, D’ambrosio, Jonathan, Acin Perez, Ana, Cachelou, Frédéric, Haffray, Pierrick, Dupont-Nivet, Mathilde, Phocas, Florence |
| Přispěvatelé: |
LALLIAS, Delphine |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Popis: |
Selective breeding is a promising solution to reduce fish farms vulnerability to heat peaks.Objectives of this study were to give a new insight on the genetic architecture of resistance toacute hyperthermia stress in rainbow trout. At 275 days post-fertilization, 1,384 fish werephenotyped for acute hyperthermia resistance and body weight. Challenged fish weregenotyped for 57K SNP and their genotypes were imputed at high-density thanks to theirparents being genotyped on a 665K SNP array. Heritability estimate of resistance to acutehyperthermia was 0.32 ± 0.04. This trait was genetically negatively correlated with body weight(-0.58 ± 0.17). The genome-wide association study revealed that resistance to acutehyperthermia is highly polygenic as altogether the 5 detected QTLs explained less than 5% ofthe genetic variance. The main QTL region explained 3% of the genetic variance and containedtwo candidate genes previously described to be associated with temperature resistance. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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