Přispěvatelé: |
CANU, Daniela, Van der Paelt, Sara, Canal-Bedia, Ricardo, Posada, Manuel, VANVUCHELEN, Marleen, Roeyers, Herbert |
Popis: |
We aimed at identifying early non-social behavioural indicators that predict later ASD. Likewise, we were interested in the moment in which non-social signs discriminate between children at elevated likelihood for ASD with a later diagnosis of ASD, and children at elevated likelihood for ASD with a typical developmental outcome. In addition, we intended to explore the developmental evolution of children's symptomatology over time. A systematic literature search was conducted for longitudinal studies on early non-social behavioural indicators among siblings at elevated likelihood for ASD. The following databases were searched: PUBMED, Web of Science, PsycINFO, CINAHL and EMBASE. The study identification process was conducted by two reviewers independently. Compared to siblings at elevated likelihood for ASD with a typical developmental outcome, siblings at elevated likelihood for ASD with later ASD show impairments in attention disengagement, in gross and fine motor development and characteristic restricted and repetitive interests and behaviours, starting at 12 months of age. Moreover, early attention disengagement exerts a predictive role towards a later ASD diagnosis, given that from 12 months siblings at elevated likelihood for ASD who will receive an independent ASD diagnosis towards 24-36 months present marked difficulties in disengaging in comparison with siblings at elevated likelihood for ASD that will not satisfy the criteria for an ASD diagnosis. The findings call for a more comprehensive vision on early indicators of ASD. Further research is needed to extend results to other behavioural domains. Open Access funding provided by Projekt DEAL. This study was funded by The Autism Spectrum Disorders in the European Union project (ASDEU). The ASDEU project has been granted by DG-SANTE, European Commission [Grant number SANCO/2014/C2/035]. Canu, D (reprint author), Hasselt Unvers, Rehabil Res Ctr REVAL, Fac Rehabil Sci, Agoralaan,Bldg A, B-3590 Diepenbeek, Hasselt, Belgium; Univ Ghent, Dept Expt Clin & Hlth Psychol, Res Dev Disorders Lab, Ghent, Belgium; Univ Freiburg, Med Ctr, Fac Med, Clin Child & Adolescent Psychiat Psychotherapy &, Freiburg, Germany. daniela.canu@uniklinik-freiburg.de |