Increasing Lateralized Motor Activity in Younger and Older Adults using Real-time fMRI during Executed Movements
| Jazyk: | angličtina |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Male
Adult real-time fMRI IMAGERY NEUROFEEDBACK Proof of Concept Study Functional Laterality Cohort Studies Young Adult motor cortex Journal Article CONTEXTUAL INTERFERENCE BRAIN ACTIVATION Humans Aged ACQUISITION Motor Cortex/diagnostic imaging Hand/physiology Motor Activity/physiology RECOVERY Middle Aged FUNCTIONAL MRI stroke Magnetic Resonance Imaging Aging/physiology ageing CORTEX ACTIVITY Female REORGANIZATION |
| Zdroj: | Neuroscience. 378:165-174 |
| ISSN: | 0306-4522 |
| DOI: | 10.1016/j.neuroscience.2017.02.010 |
| Popis: | Neurofeedback training involves presenting an individual with a representation of their brain activity and instructing them to alter the activity using the feedback. One potential application of neurofeedback is for patients to alter neural activity to improve function. For example, there is evidence that greater laterality of movement-related activity is associated with better motor outcomes after stroke; so using neurofeedback to increase laterality may provide a novel route for improving outcomes. However, we must demonstrate that individuals can control relevant neurofeedback signals. Here, we performed two proof-of-concept studies, one in younger (median age: 26years) and one in older healthy volunteers (median age: 67.5years). The purpose was to determine if participants could manipulate laterality of activity between the motor cortices using real-time fMRI neurofeedback while performing simple hand movements. The younger cohort trained using their left and right hand, the older group trained using their left hand only. In both studies participants in a neurofeedback group were able to achieve more lateralized activity than those in a sham group (younger adults: F(1,23)=4.37, p |
| Databáze: | OpenAIRE |
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