PIWIL4 Acts as a piRNA Binding, Epigenetically Active and Growth Regulatory Protein in Human Acute Myeloid Leukemia

Autor: Bamezai, S., Mulaw, M., Vegi, N., Feuring-Buske, M., Zhou, F., Rohde, C., Aravin, A., Hoell, J., Kloetgen, A., Borkhardt, A., Plass, C., Müller-Tidow, C., Rawat, V. P., Buske, C.
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Popis: Piwi proteins are critically important for maintaining the self-renewing stem cell population in lower organisms through epigenetic silencing of transposable elements via DNA methylation and H3K9me3 marks, in close interaction with a novel class of non-coding RNA called piwi interacting RNA (piRNA).
Databáze: OpenAIRE