| Autor: |
Hoogendam, A., Hofmeijer, J., Frijns, C. J.M., Heeringa, M., Schouten-Tjin A Tsoi, S. L.N.M., Jansen, P. A.F. |
| Přispěvatelé: |
Clinical Neurophysiology, TechMed Centre |
| Jazyk: |
Dutch; Flemish |
| Rok vydání: |
2002 |
| Předmět: |
|
| Zdroj: |
Nederlands tijdschrift voor geneeskunde, 146(4), 175-177. Bohn Stafleu Van Loghum |
| ISSN: |
0028-2162 |
| Popis: |
A 73-year-old woman, with tuberculosis of the large intestine, developed nausea as a side effect of the antituberculosis drugs. The nausea was treated with metoclopramide. Subsequently she developed severe medication-induced parkinsonism. As her symptoms initially mimicked a depressive disorder, drug-induced parkinsonism was only considered at a later stage. Due to drug-induced impaired function of the liver and kidney the patient had received a toxic dose of metoclopramide. Treatment with biperiden and withdrawal of the metoclopramide resulted in a reduction of the complaints within 3 months, after which the anti-tuberculosis medication could be reintroduced. Adjusting the dose of metoclopramide could possibly have prevented this severe side effect. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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