| Autor: |
Oosterhuis, J. K., van den Berg, G., Monteban-Kooistra, W. E., Ligtenberg, J. J. M., Tulleken, J. E., Zijlstra, J. G., Meertens, John |
| Přispěvatelé: |
Critical care, Anesthesiology, Peri-operative and Emergency medicine (CAPE), Vascular Ageing Programme (VAP) |
| Jazyk: |
angličtina |
| Rok vydání: |
2007 |
| Předmět: |
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| Zdroj: |
Netherlands Journal of Medicine, 65(6), 215-217. van Zuiden Communications BV. |
| ISSN: |
0300-2977 |
| Popis: |
We describe two patients with a severe Cushing's syndrome due to ectopic production of ACTH. Both patients developed a life-threatening Pneumocystis jiroveci pneumonia (PCP) shortly after treatment of the hypercortisolism was started by means of inhibition of production of glucocorticoids and glucococorticoid. receptor blockade. We presume that the restored immune response elicited the clinical symptoms of the opportunistic, previously subclinical Pneumocystis jiroveci infection. The immunocompromised. state and the delicate glucocorticoid balance in patients with a severe Cushing's syndrome necessitate a specific diagnostic and therapeutic approach. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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