| Popis: |
The clinical syndrome of dementia is best defined as an - usually at advanced age - acquired global impairment of intellect, memory and personality, but without impairment of consciousness, prominent causes of dementia are certain intrinsic degenerative diseases of the brain. The most common of these diseases is Alzheimer's disease (AD) . The pathological hallmark of AD is the presence of large amounts of so called plaques extracellular structures which involve processes of different neurons - and neurofibrillary tangles in nerve cell bodies of the cerebral cortex, hippocampus, amygdala and some subcortical brain areas. |
