CMV INFECTION AFTER ORGAN-TRANSPLANTATION - IMMUNOPATHOLOGICAL AND CLINICAL ASPECTS
Autor: | THE, TH, GREFTE, JMM, VANDERBIJ, W, VANSON, WJ, VANDENBERG, AP |
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Přispěvatelé: | Faculteit Medische Wetenschappen/UMCG, Groningen Institute for Organ Transplantation (GIOT) |
Jazyk: | angličtina |
Rok vydání: | 1994 |
Předmět: |
MONONUCLEAR-CELLS
IMMUNODEFICIENCY TRANSPLANTATION RENAL-TRANSPLANTATION CYTOMEGALOVIRUS virus diseases PERIPHERAL-BLOOD LEUKOCYTES IMMEDIATE-EARLY PROTEIN BONE-MARROW TRANSPLANTATION LIVER-TRANSPLANTATION CYTOMEGALO-VIRUS INFECTION MHC CLASS-I ENDOTHELIUM ALLOGRAFT-REJECTION INTERSTITIAL PNEUMONITIS |
Zdroj: | Netherlands Journal of Medicine, 45(6), 309-318. van Zuiden Communications BV. |
ISSN: | 0300-2977 |
Popis: | Cytomegalovirus (CMV), a member of the Herpes virus family, is a seemingly harmless infectious agent for healthy individuals. However, it is one of the most important opportunistic pathogens in immunosuppressed patients, particularly in organ transplant recipients. Due to its monocytotropic character, CMV exhibits an intimate relationship with the host immune system, and is therefore of great interest to immunologists. In this review, a summary is given of recent developments in our understanding of the interaction between CMV and the host immune system and guidelines are provided for the clinical management of this infection. |
Databáze: | OpenAIRE |
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