| Autor: |
Imhof, S. M., Mourits, M. P., Hofman, P., Zonneveld, F. W., Schipper, J., Moll, A. C., Tan, K. E. |
| Přispěvatelé: |
Other departments |
| Jazyk: |
angličtina |
| Rok vydání: |
1996 |
| Předmět: |
|
| Zdroj: |
Ophthalmology, 103(2), 263-268. Elsevier Inc. |
| ISSN: |
0161-6420 |
| Popis: |
PURPOSE: The late side effects of external beam irradiation in patients with retinoblastoma such as orbital bony growth retardation, are a serious problem in adolescence. Therefore, a quantitative study was performed to investigate the late effects of irradiation on orbital growth in patients with retinoblastoma. METHODS: The orbits of 68 patients with retinoblastoma, 52 bilateral and 16 unilateral, were divided into two treatment groups: radiotherapy alone, 77 orbits; and radiotherapy + enucleation, 43 orbits. Follow-up time was 12 to 240 months (mean, 95 months) in group 1 and 27 to 216 months (mean, 97 months) in group 2. These groups were subdivided further into age groups at which radiotherapy was given. The morphometric measurements of these groups were compared. RESULTS: The authors showed that irradiation causes a significant growth retardation when compared with the growth of nonirradiated orbits (P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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