The course of tardive dystonia in Afro Caribbean patients, a population-based study - The Curacao Extrapyramidal Syndromes Study: VII

Autor: van Harten, P. N., Matroos, G. E., Van Os, J.
Přispěvatelé: Faculteit Medische Wetenschappen/UMCG
Jazyk: angličtina
Rok vydání: 2008
Předmět:
Zdroj: Schizophrenia Research, 98(1-3), 79-83. ELSEVIER SCIENCE BV
ISSN: 0920-9964
Popis: Tardive dystonia (TDt) is a severe side effect of long-term use of antipsychotics. Previous publications suggested that TDt persist but the results are distorted by referral bias. In a population-based nine-year follow-up study (one baseline, six follow-ups) of chronic psychiatric patients (N=194) on a Caribbean island, the course of prevalent and incident TDt was measured with the Fahn-Marsden rating scale. Of the 26 patients (mean age 53.3 yrs) with TDt at baseline, 64% recovered, 20% persisted, and in 16% the course was intermittent. The severity of baseline TDt was significantly higher in persistent cases versus those who recovered (t=3.01, P
Databáze: OpenAIRE