| Autor: |
Tuininga, Y.S, Crijns, H., Kozma, S., Rabloczky, G, Jonkman, J., Lie, K. |
| Jazyk: |
angličtina |
| Rok vydání: |
1994 |
| Předmět: |
|
| Zdroj: |
International Journal of clinical Pharmacology and Therapeutics, 32(6), 278-281 |
| ISSN: |
0946-1965 |
| Popis: |
Restacorin is a recently developed effective antiarrhythmic agent with primarily class Ic properties. The present paper reviews the electrophysiologic and hemodynamic effects of this compound. The major electrophysiologic effects are a depression of V-max and an increase in AH, HV and QRS duration. The administration of restacorin does not induce significant side effects. In subjects with a normal left ventricular function, restacorin does not show negative inotropic effects. However, in patients with a decreased left ventricular function, restacorin produces a moderate negative inotropic effect. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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