Microscopic colitis: an unfamiliar but treatable disease

Autor: van der Wouden, E J, Karrenbeld, A, Kleibeuker, J H, Dijkstra, Gerard
Přispěvatelé: Guided Treatment in Optimal Selected Cancer Patients (GUTS), Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI), Translational Immunology Groningen (TRIGR), Groningen Institute for Organ Transplantation (GIOT)
Jazyk: angličtina
Rok vydání: 2009
Předmět:
Zdroj: The Netherlands Journal of Medicine, 67(2), 41-5. van Zuiden Communications BV.
ISSN: 0300-2977
Popis: Chronic diarrhoea is a frequent complaint in clinical practice. Microscopic colitis is the cause of this symptom in 10% of these cases and the prevalence is rising. To exclude microscopic colitis a colonoscopy with multiple biopsies of different regions of the colon is mandatory. A sigmoidoscopy alone is insufficient. Two histopathological types of microscopic colitis can be distinguished: collagenous colitis and lymphocytic colitis. Nowadays, there is sufficient evidence to recommend budesonide as the first-choice treatment. Bismuth can also be recommended, but this drug is not easily available in the Netherlands. Evidence of efficacy of other drugs is scant.
Databáze: OpenAIRE