Albuminuria during the screening for diabetes in a semi-rural area (Kisantu City, DR Congo)

Autor: Makulo, Rissassi, Jr., Nseka, Mangani Nazaire, Jadoul, Michel, Mvitu, Moise, Muyer, Muel Telo, Kimenyembo, Wivine, Mandja, Makasa, Bieleli, Ebanz'Osongo, Mapatano, Mala Ali, Epira, Francois Bompeka, Sumaili, Ernest Kiswaya, Kaimbo, W. K., Nge, Okwe, Buntinx, Frank, Muls, Erik
Přispěvatelé: Family Medicine, RS: CAPHRI School for Public Health and Primary Care
Jazyk: angličtina
Rok vydání: 2010
Předmět:
Zdroj: Néphrologie & Thérapeutique, 6(6), 513-519. Elsevier Masson
ISSN: 1769-7255
Popis: Objectives. - To determine the prevalence of microalbuminuria, macroalbuminuria and renal insufficiency at the time of screening for diabetes and impaired fasting glucose in the semi-rural area of Kisantu/DR Congo, and to identify determinants of pathological urinary albumin excretion (UAE). Methods. - Step 1: diabetes (81 cases) and impaired fasting glucose (148 cases) tracking in the population (1898 subjects selected by a systematic survey). Step 2: urinary albumin and serum creatinine were measured and glomerular filtration rate was estimated (modification of the diet in renal disease [MDRD] equation). The determinants of pathological UAE were assessed by logistic regression. Results. - The prevalence of macroalbuminuria and microalbuminuria in diabetes was 12.0 and 45.2% respectively versus 0 and 13.7% in impaired fasting glucose. Determinants of pathological UAE were: diabetes (adjusted OR [aOR]: 7.01; 95% CI: 3.48-14.11), central obesity (aOR: 2.36 [1.16-4.80]), age less that 60 years (aOR: 2.12 [1.05-4.40]), hypertension [aOR: 3.30 (1.39-7.82)] and diabetic retinopathy (aOR: 3.12 [1.54-6.26]). Renal insufficiency (MDRD
Databáze: OpenAIRE