Sodium MRI measurement of ion convection-diffusion in swelling gels
| Autor: | Huyghe, J.M.R.J., Roos, R.W., Huinink, H.P., Pel, L., Schrefler, B., Onate, E. |
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| Přispěvatelé: | Soft Tissue Biomech. & Tissue Eng., Transport in Permeable Media |
| Jazyk: | angličtina |
| Rok vydání: | 2007 |
| Zdroj: | Proceedings of the International Conference on Computational Methods for Coupled Problems in Science and Engineering (COUPLED PROBLEMS 2007) 21-23 May 2007, Santa Eualia, Ibiza, Spain, MoM03-1/4 STARTPAGE=MoM03;ENDPAGE=1/4;TITLE=Proceedings of the International Conference on Computational Methods for Coupled Problems in Science and Engineering (COUPLED PROBLEMS 2007) 21-23 May 2007, Santa Eualia, Ibiza, Spain |
| Popis: | Convection diffusion of ions plays a major role in munerous cellular processses in biology. A quadriphasic mixture model has been developed to model the coupling between diffusion, convection, swelling and deformation in gels and tissues. Sodium and hydrogen MRI is used to measure convection-diffusion of sodium ions in homogenous ionised gels subject to swelling. A sodium chloride concentration jump from 0.5 M to 0 M at the boundary of a pAA sample is applied. Subsequently, sodium and hydrogen levels are measured in the sample for 5 days. Then the boundary condition is reversed and measurement is continued for another 5 days. The quadriphasic mixture model is fitted to the experimental data to estimate the di??usion coefficient of sodium and chloride. The best fit results were obtained forDNa = 1:1510-5cm2=s and for DCl = 2:1510-5cm2=s. Different time constants were observed for the swelling and deswelling. |
| Databáze: | OpenAIRE |
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