Fatale pneumonitis door oseltamivir-resistente nieuwe influenza A(H1N1) bij een intensive-carepatiënt

Autor: Aardema, Heleen, Tulleken, Jaap E, van den Biggelaar, Ries J M, Wolters, Bert A, de Jager, Corine M, Boucher, Charles A B, Riezebos-Brilman, Annelies
Přispěvatelé: Microbes in Health and Disease
Jazyk: Dutch; Flemish
Rok vydání: 2010
Předmět:
Zdroj: Nederlands Tijdschrift voor Geneeskunde, 154. NLM (Medline)
ISSN: 0028-2162
Popis: A 58-year-old man was submitted to our intensive care ward with respiratory failure due to pneumonitis. He had previously been treated for non-Hodgkin lymphoma by autologous stem cell transplantation, as a result of which bone marrow function was reduced. Further analysis showed infection with new influenza A(H1N1); typing revealed an oseltamivir-resistant subpopulation (H275Y). The patient was treated with oseltamivir and intravenously with zanamivir, but died of respiratory disease progression. This is the first published case of oseltamivir-resistant new influenza A(H1N1) infection in the Netherlands.
Databáze: OpenAIRE