Localization of X chromosome short arm markers relative to synovial sarcoma- and renal adenocarcinoma-associated translocation breakpoints

Autor:	Sinke, R J, de Leeuw, B, Janssen, H A, Weghuis, D O, Suijkerbuijk, R F, Meloni, A M, Gilgenkrantz, S, Berger, W, Ropers, H H, Sandberg, A A
Jazyk:	angličtina
Rok vydání:	1993
Předmět:	Genetic Markers Male X Chromosome Chromosome Mapping Hybrid Cells Translocation Genetic Blotting Southern Sarcoma Synovial Cricetulus Chromosomes Human Pair 1 Cricetinae Tumor Cells Cultured Animals Humans Chromosomes Human Pair 18 Carcinoma Renal Cell
Zdroj:	HUMAN GENETICS, 92(3), 305-8. SPRINGER
ISSN:	0340-6717
Popis:	A series of thirteen different DNA markers was mapped relative to papillary renal cell carcinoma- and synovial sarcoma-associated translocation breakpoints in Xp11.2 using a panel of tumor-derived somatic cell hybrids in conjunction with Southern blot analysis. Our results indicate that the two translocation breakpoints differ from each other and that the chromosomal break in t(X;1)-positive papillary renal cell carcinoma is located between the markers PFC-TIMP-OATL1-SYP-TFE3 and DXS226-DXS146-DXS255-OATL2-DXS14. In addition, our current breakpoint analysis has resulted in a revision of the regional localization of the proximal Xp marker DXS226.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=narcis______::7e14e5215a1caac456a90d9b684eca25 https://research.rug.nl/en/publications/beb590a9-563a-47cc-82d6-cca82c817bc8 Zobrazit plný text záznamu Full text from SpringerLink