| Autor: |
Rupp, Ines, Boshuizen, Hendriek C., Jacobi, Catharina E., Dinant, Huibert J., van den Bos, Geertrudis A. M. |
| Přispěvatelé: |
Public and occupational health, Clinical Immunology and Rheumatology |
| Jazyk: |
angličtina |
| Rok vydání: |
2004 |
| Předmět: |
|
| Zdroj: |
Arthritis and rheumatism, 51(4), 578-585. John Wiley and Sons Inc. |
| ISSN: |
0004-3591 |
| Popis: |
Objective. To multidimensionally assess fatigue in rheumatoid arthritis (RA) and to evaluate the impact of fatigue on health-related quality of life (HRQOL). Methods. The study was conducted in 1999 among 490 RA patients with varying disease duration. Fatigue was measured with the Multidimensional Fatigue Inventory (MFI-20) and HRQOL with a validated Dutch version of the RAND 36-Item Health Survey. We evaluated the impact of fatigue on HRQOL by multiple linear regression analyses taking into account RA-related pain and depressive symptoms. Results. Different aspects of fatigue selectively explained different dimensions of HRQOL. The MFI-20 was entered last to the linear regression models, resulting in an additional increase of explained variance of 1% (mental health) to 14% (vitality). Conclusion. The multidimensional portrayal of RA-related fatigue can be used to develop intervention strategies targeted to specific aspects of fatigue. Fatigue, supplementary to RA-related pain and depressive symptoms, appears to be a feasible and treatable target in the clinical management of RA to increase HRQOL |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
Plný text