Cataract after total body irradiation and bone marrow transplantation: degree of visual impairment

Autor: van Kempen-Harteveld, M. Loes, Struikmans, Henk, Kal, Henk B., van der Tweel, Ingeborg, Mourits, Maarten P., Verdonck, Leo F., Schipper, Jan, Battermann, Jan J.
Přispěvatelé: Other departments
Jazyk: angličtina
Rok vydání: 2002
Předmět:
Zdroj: International journal of radiation oncology, biology, physics, 52(5), 1375-1380. Elsevier Inc.
ISSN: 0360-3016
Popis: PURPOSE: To assess the degree of visual impairment as a result of cataract formation after total body irradiation (TBI) for bone marrow transplantation. METHODS AND MATERIALS: The data from 93 patients who received TBI in 1 or 2 fractions as a part of their conditioning regimen for bone marrow transplantation were analyzed with respect to the degree of visual impairment as a result of cataract formation. The probability to develop severe visual impairment (SVI) was determined for all patients, and the degree of visual impairment was assessed for 56 patients with stabilized cataract, using three categories: no, mild, or severe. RESULTS: For all 93 patients, the probability of developing a cataract causing SVI was 0.44. For allogeneic patients, it was 0.33 without and 0.71 with steroid treatment (p
Databáze: OpenAIRE