Localization Study of Co-Phthalocyanines in Cells by Raman Micro(spectro)scopy

Autor: Arzhantsev, S.Y., Chikishev, A.Y., Koroteev, N.I., Greve, Jan, Otto, Cornelis, Sijtsema, N.M.
Přispěvatelé: Faculty of Science and Technology, Medical Cell Biophysics
Rok vydání: 1999
Předmět:
Zdroj: Journal of raman spectroscopy, 30(3), 205-208. Wiley
ISSN: 0377-0486
Popis: An investigation of intracellular localization of Co-phthalocyanines is reported. The Raman images of K562 cells stained with phthalocyanine were acquired. To understand the peculiarities of the Raman images, measurements were performed at different z-axis positions. The intracellular concentration of phthalocyanine was estimated. A colocalization study was carried out using the fluorescence probes FITC-dextran and acridine orange by means of Raman and fluorescence microscopy. Partial colocalization with both probes was revealed.
Databáze: OpenAIRE