Association between blood pressure levels over time and brain atrophy in the elderly

Autor:	den Heijer, T, Skoog, [No Value], Oudkerk, M, de Leeuw, FE, de Groot, JC, Hofman, A, Breteler, MMB
Jazyk:	angličtina
Rok vydání:	2003
Předmět:	ALZHEIMERS-DISEASE atrophy HYPERTENSION ABNORMALITIES brain DEMENTIA blood pressure epidemiology WHITE-MATTER LESIONS ROTTERDAM SCAN NEUROFIBRILLARY TANGLES HYPOPERFUSION
Zdroj:	Neurobiology of Aging, 24(2):PII S0197-4580(02)00088-X, 307-313. ELSEVIER SCIENCE INC
ISSN:	0197-4580
Popis:	The relation between blood pressure level and degree of global brain atrophy is equivocal. We evaluated past and present blood pressure levels and change in blood pressure over 20 years in relation to the degree of cortical atrophy on magnetic resonance imaging (MRI). In 1995-1996, we measured blood pressure and performed MRI in 1077 nondemented elderly (age 60-90 years). For 513 of these, we had information on a blood pressure level 20 years before. The degree of cortical atrophy was semi-quantitatively scored (range 0-15). In late life, a high (greater than or equal to 90 mmHg) and low (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=narcis______::64218ba7cdcf7d696d88808be33d5e56 https://research.rug.nl/en/publications/383fec82-cb21-46d2-81b0-43a251ca5d08 Zobrazit plný text záznamu Full Text from ScienceDirect