The application of multiplexed assay systems for molecular diagnostics

Autor: Schwarz, E, Beveren, JM, Guest, PC, Izmailov, R, Bahn, Sabine
Přispěvatelé: Psychiatry, Neurosciences
Rok vydání: 2011
Zdroj: International Review of Neurobiology, 101, 259-278. Academic Press
ISSN: 0074-7742
Popis: For decades, the diagnosis of schizophrenia and other psychiatric disorders has relied on subjective assessments such as Diagnostic and Statistical Manual criteria. There is now increasing interest in the identification of altered molecular patterns in blood and other accessible body fluids that can be used to help identify, stratify and monitor psychiatric patients. Since shorter periods of psychosis are associated with a better prognosis, an accurate molecular test may lead to early intervention and thereby improve patient outcomes. In addition, such a test would open up the possibility to stratify more accurately the disease and could represent a novel translational medicine tool, which is crucial for the discovery and development of more efficacious therapies.
Databáze: OpenAIRE