Autor: |
Mets, M.A.J., Volkerts, E.R., Dunnebier, E.A., de Senerpont Domis, L.M., Olivier, B., Verster, J.C., Dierexperimenteel, Humaan, Dep Farmaceutische wetenschappen |
Jazyk: |
angličtina |
Rok vydání: |
2008 |
Zdroj: |
The Open Allergy Journal, 1, 19. Bentham Science Publishers B.V. |
ISSN: |
1874-8384 |
Popis: |
Background: Seasonal allergic rhinitis (SAR) has shown to affect quality of life and impair cognitive functioning. Objective: The objective of this study was to compare driving ability, memory, and psychomotor performance during grass pollen season with winter season in untreated patients with SAR. Methods: Patients with SAR were trained and tested during the grass pollen season (summer) and winter. An on-the-road driving test during normal traffic conditions was performed. Primary parameter is the Standard Deviation of Lateral Position (SDLP), i.e. the weaving of the car. In addition, a word learning test and continuous performance test were performed and quality of life was assessed. Patients were included if in winter the Total 5-Symptoms Score (T5SS) was < 3 and in summer the T5SS was > 3. Results: 70 patients were recruited of which 22 started the study. Fifteen patients completed the study of which 11 met the inclusion criteria. These 11 patients had a mean T5SS of 6.8 in summer and 0.6 in winter. Patient reported a significantly reduced overall quality of life during grass pollen season (p |
Databáze: |
OpenAIRE |
Externí odkaz: |
|