Autor: |
Bakker, SJL, ter Maaten, JC, Popp-Snijders, C, Slaets, JPJ, Heine, RJ, Gans, ROB |
Přispěvatelé: |
Health Psychology Research (HPR), Groningen Institute for Organ Transplantation (GIOT), Lifestyle Medicine (LM), Groningen Kidney Center (GKC) |
Jazyk: |
angličtina |
Rok vydání: |
2001 |
Předmět: |
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Zdroj: |
Journal of Clinical Endocrinology and Metabolism, 86(3), 1206-1211. ENDOCRINE SOC |
ISSN: |
0021-972X |
Popis: |
High levels of TSH are associated with an increased cardiovascular risk. Many cardiovascular risk factors cluster within the insulin resistance syndrome. It is not known whether levels of TSH cluster as well. We conducted this research to test the hypothesis that TSH, insulin sensitivity, and levels of low density lipoprotein cholesterol (LDL-C) and high density lipoprotein cholesterol (HDL-C) are interdependent in euthyroid subjects. Levels of TSH, free thyroid hormone, and serum Lipids were measured in fasting serum samples taken before performance of a hyperinsulinemic euglycemic clamp to assess insulin sensitivity in 46 healthy euthyroid subjects with a mean TSH of 1.8 +- 0.7 mU/L. Significant age- and sex-adjusted partial correlations of TSH with LDL-C (r = 0.48; P |
Databáze: |
OpenAIRE |
Externí odkaz: |
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