| Autor: |
Damen, Bram, Cloetens, Lieselotte, Broekaert, Willem F., Francois, Isabelle, Lescroart, Olivier, Trogh, Isabel, Arnaut, Filip, Welling, Gjalt W., Wijffels, Jan, Delcour, Jan A., Verbeke, Kristin, Courtin, Christophe M. |
| Jazyk: |
angličtina |
| Rok vydání: |
2012 |
| Předmět: |
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| Zdroj: |
The Journal of Nutrition, 142(3), 470-477. Oxford University Press |
| ISSN: |
0022-3166 |
| Popis: |
Arabinoxylan oligosaccharides (AXOS) are studied as food compounds with prebiotic potential. Here, the impact of consumption of breads with in situ-produced AXOS on intestinal fermentation and overall gastrointestinal characteristics was evaluated in a completely randomized, double-blind, controlled, cross-over study. Twenty-seven healthy volunteers consumed 180 g of wheat/rye bread with or without in situ-produced AXOS (WR+ and WR-, respectively) daily for 3 wk. Consumption of WR+ corresponded to an AXOS intake of similar to 2.14 g/d. Refined wheat flour bread without AXOS (WT) (180 g/d) was provided during the 3-wk run-in and wash-out periods. At the end of each treatment period, participants collected urine for 48 h as well as a feces sample. Additionally, all participants completed a questionnaire about stool characteristics and gastrointestinal symptoms during the last week of each period. Urinary phenol and p-cresol excretions were significantly lower after WR+ intake compared to WR-. Consumption of WR+ significantly increased fecal total SCFA concentrations compared to intake of W-. The effect of WR+ intake was most pronounced on butyrate, with levels 70% higher than after consumption of W- in the run-in or wash-out period. Consumption of WR+ tended to selectively increase the fecal levels of bifidobacteria (P = 0.06) relative to consumption of W-. Stool frequency increased significantly after intake of WR+ compared to WR-. In conclusion, consumption of breads with in situ-produced AXOS may favorably modulate intestinal fermentation and overall gastrointestinal properties in healthy humans. J. Nutr. 142: 470-477, 2012. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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