| Autor: |
Rudiger, T, Jaffe, ES, Delsol, G, deWolf-Peeters, C, Gascoyne, RD, Georgii, A, Harris, NL, Kadin, ME, MacLennan, KA, Poppema, S, Stein, H, Weiss, LE, Muller-Hermelink, HK |
| Jazyk: |
angličtina |
| Rok vydání: |
1998 |
| Předmět: |
|
| Zdroj: |
Annals of Oncology, 9, 31-38. Oxford University Press |
| ISSN: |
0923-7534 |
| Popis: |
Despite advances in immunohistochemistry and molecular biology, the distinction between classical Hodgkin's lymphoma and related diseases such as nodular lymphocyte-predominant Hodgkin's disease, T-cell rich large B-cell lymphoma or anaplastic large cell lymphoma has remained difficult in rare cases. Lack of clear-cut diagnostic criteria represents a problem for both the pathologist and the clinician. To delineate this 'grey zone' between classical Hodgkin's lymphoma and non-Hodgkin's lymphoma (NHL) and to develop criteria for classification of such cases, 12 expert hematopathologists each submitted one to five borderline cases to a workshop. Cases were reviewed and classified at a multiheaded microscope and criteria were established for the diagnosis of questionable cases. Well established entities such as classical Hodgkin's lymphoma? anaplastic large-cell lymphoma and TCRBCL were defined more strictly and cases with unusual morphology or antigen expression could be identified. A distinctive subset of cases representing mediastinal large B-cell lymphomas with features of Hodgkin's lymphoma was identified. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
