IN-LINE ANALYSIS OF LIQUIDS IN MICROFLUIDIC CHANNELS WITH LINE-FOCUSED RAMAN SPECTROSCOPIC IMAGING

Autor:	Klement, W. J.Niels, Browne, Wesley R., Verpoorte, Elisabeth
Přispěvatelé:	Pharmaceutical Analysis, Molecular Inorganic Chemistry, Medicinal Chemistry and Bioanalysis (MCB)
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	Raman spectroscopy imaging label-free optical detection sCMOS
Zdroj:	MicroTAS 2021-25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, 1607-1608 STARTPAGE=1607;ENDPAGE=1608;TITLE=MicroTAS 2021-25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Popis:	Determining concentration profiles in microfluidic channels is essential in validating the performance of structures designed to control mixing of converging solvent streams. Here we report the use of line focused illumination to provide simultaneous spatially resolved Raman spectra. An sCMOS sensor is used to overcome the cross talk encountered during spectral readout with CCD sensors. We show that z-confocality presents a limit to the spatial resolution that can be achieved with this approach.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=narcis______::2ad4f6ad9004640a40fdec066a4ed728 https://research.rug.nl/en/publications/920e68ca-0d5f-4a36-9c45-eb5fb98231bc Zobrazit plný text záznamu