SPECT in early- and late-onset Alzheimer's disease

Autor: Weinstein, H. C., Hijdra, A., van Royen, E. A., Derix, M. M., Walstra, G., Jonker, C.
Přispěvatelé: Other departments
Jazyk: angličtina
Rok vydání: 1991
Zdroj: Annals of the New York Academy of Sciences, 640, 72-73. Wiley-Blackwell
ISSN: 0077-8923
Popis: We assessed with SPECT the influence of age of onset in Alzheimer's disease in patients who were matched for severity of disease with early and late onset of the disease. Twenty-six patients, severity-matched according to scores on Mini-Mental State Examination, were compared to nine controls. Comparison of the temporoparietal cerebellar ratio (TPC) revealed a statistically significantly lower ratio in the early-onset group compared to the late-onset group of patients. These results are in agreement with other imaging, structural, and neurochemical studies, supporting the view of heterogeneity of Alzheimer's disease according to age of onset
Databáze: OpenAIRE