| Autor: |
Kolli, Kranthi K., van de Hoef, Tim P., Effat, Mohamed A., Banerjee, Rupak K., Peelukhana, Srikara V., Succop, Paul, Leesar, Massoud A., Imran, Arif, Piek, Jan J., Helmy, Tarek A. |
| Přispěvatelé: |
Cardiology, Amsterdam Cardiovascular Sciences |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
|
| Zdroj: |
Catheterization and cardiovascular interventions, 87(2), 273-282. Wiley-Liss Inc. |
| ISSN: |
1522-1946 |
| Popis: |
Functional assessment of intermediate coronary stenosis during cardiac catheterization is conducted using diagnostic parameters like fractional flow reserve (FFR), coronary flow reserve (CFR), hyperemic stenosis resistance index (HSR), and hyperemic microvascular resistance (HMR). CDP (ratio of pressure drop across a stenosis to distal dynamic pressure), a nondimensional index derived from fundamental fluid dynamic principles, based on a combination of intracoronary pressure, and flow measurements may improve the functional assessment of coronary lesion severity. Patient-level data pertaining to 350 intracoronary pressure and flow measurements across coronary stenoses was assessed to evaluate CFR, FFR, HSR, HMR, and CDP. CDP was calculated as (ΔP)/(0.5 × ρ × APV(2)). The density of blood (ρ) was assumed to be 1.05 g/cm(3). The correlation of current diagnostic parameters (CFR, FFR, HSR, and HMR) with CDP was evaluated. The receiver operating characteristic (ROC) curve was used to identify the optimal cut-off point of CDP, corresponding to the clinically used cut-off values (FFR = 0.80 and CFR = 2.0). CDP correlated significantly with FFR (r = 0.81, P 25.4. CDP also correlated significantly (r = 0.98, P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
Plný text