| Autor: |
Mönch, Dina, Reinders, Marlies E.J., Hoogduijn, Martin J., Dahlke, Marc Hendrik |
| Přispěvatelé: |
Internal Medicine |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Zdroj: |
Cells, 12(4):559. Multidisciplinary Digital Publishing Institute (MDPI) |
| ISSN: |
2073-4409 |
| Popis: |
The use of mesenchymal stromal cells (MSCs) for clinical application is intensively investigated for a variety of areas, such as bone repair, haematological and autoimmune diseases, and solid organ transplantation. Moreover, increasing insights into their mechanism of actions revealed a lively (paracrine) interaction between MSCs and recipient (immune) cells and identified novel mediators such as extracellular vesicles (EVs). Both paracrine signals and EVs have been shown to play a role in the effects of MSCs and may potentially complement MSC-based therapies or represent therapeutic alternatives. This Special Issue of Cells is devoted to the many aspects of MSC-based therapy and includes original data papers and reviews on preclinical models, clinical studies, as well as MSC manufacturing protocols. [...] |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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