| Autor: |
McClean, A., Morgan, M.D., Basu, N., Bosch, J.A., Nightingale, N., Jones, D., Harper, L. |
| Přispěvatelé: |
FMG, Klinische Psychologie (Psychologie, FMG), Brain and Cognition |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Zdroj: |
Arthritis Care & Research, 68(9), 1332-1339. John Wiley and Sons Inc. |
| ISSN: |
2151-464X |
| Popis: |
Objective. This study investigated differences in cardiorespiratory fitness, muscular function, perceived exertion, and anxiety/depression between patients and healthy controls (HCs) and assessed which of these variables may account for the fatigue experienced by patients. Methods. Fatigue was measured in 48 antineutrophil cytoplasmic antibody–associated vasculitis patients and 41 healthy controls using the Multidimensional Fatigue Inventory (MFI-20), focusing on the physical component. Quality of life, anxiety/depression, and sleep quality were assessed by validated questionnaires. Muscle mass was measured by dual-energy x-ray absorptiometry scan, strength as the maximal voluntary contraction (MVC) force, and endurance as sustained isometric contraction at 50% MVC of the quadriceps. Voluntary activation was assessed by superimposed electrical stimulation. Cardiorespiratory fitness (_Vo2 max and oxygen pulse [O2 pulse]) and perceived exertion (Borg scale) were measured during progressive submaximal exercise. Results. Patients reported elevated physical fatigue scores compared to HCs (patients MFI-20 physical 13 [interquar-tile range (IQR) 8–16], HCs MFI-20 physical 5.5 [IQR 4–8]; P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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