| Autor: |
Poele , te, Esther, Kamps, WA, Tamminga, RYJ, Leew, JA, Postma, A, de Bont, ESJM |
| Přispěvatelé: |
Damage and Repair in Cancer Development and Cancer Treatment (DARE), Stem Cell Aging Leukemia and Lymphoma (SALL) |
| Jazyk: |
angličtina |
| Rok vydání: |
2005 |
| Předmět: |
|
| Zdroj: |
Journal of pediatric hematology oncology, 27(11), 627-629. LIPPINCOTT WILLIAMS & WILKINS |
| ISSN: |
1077-4114 |
| Popis: |
Chemotherapy-induced neutropenia is a major dose-limiting side effect of intensive chemotherapy in cancer patients. Recently, pegfilgrastim (a product with a long half-life, resulting in once-per-cycle dosage) was introduced to prevent neutropenia in adults. The authors report 32 episodes of pegfilgrastim use in seven pediatric cancer patients to diminish chemotherapy-induced neutropenia. Feasibility was assessed by adherence to treatment protocol and safety was assessed by adverse effects. There were only two treatment delays (6%) due to neutropenia. No short-term adverse effects were recorded. The use of pegfilgrastim is feasible in pediatric cancer patients, without short-term adverse effects or major treatment delay due to neutropenia. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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