Buikklachten en neurologische symptomen als vroege manifestatie van longkanker: een uiting van het anti-Hu-syndroom
| Autor: | Wymenga, A N M, Slebos, D J, van der Naalt, J, van Putten, J W G, Peters, F T M |
|---|---|
| Jazyk: | Dutch; Flemish |
| Rok vydání: | 2003 |
| Předmět: |
Lung Neoplasms/diagnosis
Nervous System Diseases/diagnosis RNA-Binding Proteins/immunology Middle Aged Paraneoplastic Syndromes/diagnosis Prognosis Diagnosis Differential Nerve Tissue Proteins/immunology ELAV Proteins Carcinoma Small Cell/diagnosis Humans Female Gastrointestinal Diseases/diagnosis Gastrointestinal Motility Aged Autoantibodies/analysis |
| Zdroj: | Nederlands Tijdschrift voor Geneeskunde, 147(13), 616-619. NLM (Medline) |
| ISSN: | 0028-2162 |
| Popis: | In two patients, women aged 73 and 46 years, gastrointestinal symptoms were initially not recognised as a paraneoplastic syndrome due to small-cell lung cancer. This led to redundant diagnostics as well as a delay in final diagnosis. The anti-Hu syndrome is characterised by the presence of anti-Hu antibodies and neurological symptoms. About a quarter of the patients with the anti-Hu syndrome will develop gastrointestinal motility disorders in the course of their illness. The primary tumour is usually a small-cell lung cancer. Whereas the presence of anti-Hu antibodies appears to be beneficial for the oncological prognosis, the neurological outcome is less favourable. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|