| Autor: |
Tatu, Elena Niculet, Carmen Bobeica, Cristian Onisor, Gabriela Gurau, Aurel Nechita, Diana Sabina Radaschin, Dana Tutunaru, Laura Bujoreanu-Bezman, Alin Laurentiu |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Life; Volume 13; Issue 6; Pages: 1406 |
| ISSN: |
2075-1729 |
| DOI: |
10.3390/life13061406 |
| Popis: |
Basal cell carcinoma (BCC) is a malignant tumor with a rising incidence and is the beneficiary of several innovative evaluation techniques. Histopathology remains the gold standard for assessment, having the possibility of addressing multiple high-risk factors such as perineural invasion (PNI). The current study included a number of 244 BCC patients and targeted the identification of positive PNI and its suggestive signs, and whether they correlated or not with other high-risk tumor signs. PNI was found in 20.1% of patients, with 30.7% of patients having perineural chronic inflammation (PCI), which is a suggestive sign of PNI. PNI was also found in larger tumors, with deeper Clark levels, in high-risk BCCs and high-grade tumors. PNI and PCI are both important for pathology reporting, aiding in treatment choice and further patient management, with possibly positive outcomes concerning morbidity and mortality. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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